Quick Answer: Why Has Venlafaxine Been Discontinued In The US?

Effexor is made by Wyeth Pharmaceuticals, Inc.

and was approved by the U.S.

Food and Drug Administration (FDA) in 1993.

Effexor was discontinued because the newer time-released Effexor XR formula can be taken once daily and causes less nausea than the original formula.

What does venlafaxine do to the brain?

It works by increasing and regulating the levels of two different neurotransmitters in the brain. These are norepinephrine, also called noradrenaline, and serotonin. At low doses, venlafaxine prevents serotonin reuptake. At higher doses, it inhibits both serotonin and noradrenaline reuptake.

Is venlafaxine a narcotic?

Venlafaxine is structurally and pharmacologically related to the atypical opioid analgesic tramadol, and more distantly to the newly released opioid tapentadol, but not to any of the conventional antidepressant drugs, including tricyclic antidepressants, SSRIs, MAOIs, or RIMAs.

When was venlafaxine approved by the FDA?

Effexor was approved for the treatment of depression in 1993. Effexor increases the levels of both serotonin and norepinephrine (two neurotransmitters though to cause the symptoms of depression) in the brain. Effexor’s latest approval is for the treatment of anxiety disorder.

What happens when you stop taking Effexor?

Do not stop taking venlafaxine, even when you feel better. Stopping venlafaxine abruptly may result in one or more of the following withdrawal symptoms: irritability, nausea, feeling dizzy, vomiting, nightmares, headache, and/or paresthesias (prickling, tingling sensation on the skin).